Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50003272 Sort by
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nahda University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 40nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human His6-tagged MEK1 as substrate preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nahda University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 70nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Nahda University

Curated by ChEMBL
LigandPNGBDBM50468896(CHEMBL4279008)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nahda University

Curated by ChEMBL
LigandPNGBDBM50468892(CHEMBL4289274)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nahda University

Curated by ChEMBL
LigandPNGBDBM50468891(CHEMBL4286943)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nahda University

Curated by ChEMBL
LigandPNGBDBM50468896(CHEMBL4279008)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human His6-tagged MEK1 as substrate preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nahda University

Curated by ChEMBL
LigandPNGBDBM50468895(CHEMBL4290355)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nahda University

Curated by ChEMBL
LigandPNGBDBM50468894(CHEMBL4282482)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nahda University

Curated by ChEMBL
LigandPNGBDBM50468893(CHEMBL4286998)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed