Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50002481
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459051(CHEMBL4209672)
Affinity DataIC50: 501nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in MDCK2 cells incubated for 30 mins measured at 60 secs interval for 120 mins by Hoechst 33342 staini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 526nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM32628(Fumitremorgin C | FTC)
Affinity DataIC50: 731nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459046(CHEMBL4213215)
Affinity DataIC50: 880nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459050(CHEMBL1946989)
Affinity DataIC50: 940nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux measured after 30 mins by fluorescence as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459043(CHEMBL4206629)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459045(CHEMBL4216590)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux measured after 30 mins by fluorescence as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459040(CHEMBL4209477)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459038(CHEMBL4206326)
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459048(CHEMBL4203520)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459039(CHEMBL4202610)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459047(CHEMBL4204938)
Affinity DataIC50: 4.08E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459044(CHEMBL4208261)
Affinity DataIC50: 6.65E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459041(CHEMBL4216382)
Affinity DataIC50: 6.73E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459037(CHEMBL4215970)
Affinity DataIC50: 8.76E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459042(CHEMBL4210356)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia-Sede Bogot£

Curated by ChEMBL
LigandPNGBDBM50459049(CHEMBL4204291)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed