Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50003293
TargetVitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/Vitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  1.60nMAssay Description:Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/Vitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469127(CHEMBL4288947)
Affinity DataEC50:  6.40nMAssay Description:Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/Vitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50441900(CHEMBL2434990)
Affinity DataEC50:  6.80nMAssay Description:Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/Vitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469128(CHEMBL4290851)
Affinity DataEC50:  38nMAssay Description:Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469127(CHEMBL4288947)
Affinity DataIC50: 89nMAssay Description:Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50441900(CHEMBL2434990)
Affinity DataIC50: 115nMAssay Description:Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469128(CHEMBL4290851)
Affinity DataIC50: 125nMAssay Description:Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469128(CHEMBL4290851)
Affinity DataIC50: 650nMAssay Description:Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469127(CHEMBL4288947)
Affinity DataIC50: 970nMAssay Description:Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50441900(CHEMBL2434990)
Affinity DataIC50: 4.30E+3nMAssay Description:Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50: 6.43E+3nMAssay Description:Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed