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Report error Found 363 Enz. Inhib. hit(s) with all data for entry = 50009704 Sort by
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM117170(US8648092, 101)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of recombinant human GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells Fluor-de-lys as substrate measured after 2 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM117141(US8648092, 72)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of recombinant human GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells Fluor-de-lys as substrate measured after 2 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM117146(US8648092, 77)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of recombinant human GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells Fluor-de-lys as substrate measured after 2 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531385(CHEMBL4568666)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of recombinant human HDAC1 expressed in NIH/3T3 cells using [3H]acetyl histone as substrate measured after 15 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531393(CHEMBL4438063)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531382(CHEMBL4455057)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531391(CHEMBL4472220)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of recombinant human GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells Fluor-de-lys as substrate measured after 2 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531357(CHEMBL4543166)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531378(CHEMBL4571133)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of recombinant human HDAC1 expressed in NIH/3T3 cells using [3H]acetyl histone as substrate measured after 15 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531384(CHEMBL4574244)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531374(CHEMBL4467135)
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531398(CHEMBL4454463)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531392(CHEMBL4441675)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant full-length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using fluorescent-labelled...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM218227(BDBM50531386 | US9249087, Table 1 , Compound 4)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant full-length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using fluorescent-labelled...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant full-length human HDAC6 using RHKK(Ac) as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531339(CHEMBL4577299)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human HDAC6 using fluorogenic HDAC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531365(CHEMBL4438404)
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant full-length human HDAC1 using RHKK(Ac) as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531329(CHEMBL4082995)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant full-length human HDAC6 using RHKK(Ac) as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50314637((E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531365(CHEMBL4438404)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531366(CHEMBL4543038)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531341(CHEMBL4531108)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human HDAC6 using fluorogenic HDAC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50309931(6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-te...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human HDAC4 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531365(CHEMBL4438404)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50252396(CHEMBL4077645)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human HDAC6 using Boc Lys(Ac)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531356(CHEMBL4455552)
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531330(CHEMBL4467160)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human HDAC4 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531320(CHEMBL4469098)
Affinity DataIC50: 6nMAssay Description:Inhibition of human HDAC6 using fluorogenic HDAC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50314627((E)-N-Hydroxy-3-{4-[3-(2-methyl-1H-indol-3-yl)pipe...)
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50314636((E)-N-Hydroxy-3-{4-[3-(2-phenyl-1H-indol-3-yl)pipe...)
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531348(CHEMBL4456028)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant human His-tagged HDAC6 expressed in baculovirus infected insect cells using Boc Lys(Ac)-AMC as substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531355(CHEMBL4531791)
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531366(CHEMBL4543038)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant human His-tagged HDAC6 expressed in baculovirus infected insect cells using Boc Lys(Ac)-AMC as substrate preincubated for 5...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531318(CHEMBL4557665)
Affinity DataIC50: 8nMAssay Description:Inhibition of human HDAC6 using fluorogenic HDAC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50492422(CHEMBL2401844)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531317(CHEMBL4445312)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human HDAC6 using fluorogenic HDAC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531366(CHEMBL4543038)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human HDAC6 using fluorogenic HDAC substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531342(CHEMBL4283105)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human HDAC6 using fluorogenic HDAC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GST-fused HDAC1 expressed in HEK293 cells Fluor-de-lys as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531330(CHEMBL4467160)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531319(CHEMBL4450128)
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC6 using fluorogenic HDAC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 11(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant full-length human HDAC11 using RHKK(Ac) as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50309931(6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-te...)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531367(CHEMBL4452333)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531349(CHEMBL4451082)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human His-tagged HDAC6 expressed in baculovirus infected insect cells using Boc Lys(Ac)-AMC as substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50492416(CHEMBL2401847)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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