Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50002521
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459685(CHEMBL4209785)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459697(CHEMBL4214693)
Affinity DataIC50: 360nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459699(CHEMBL4215206 | US12006283, Example 10)
Affinity DataIC50: 600nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459684(CHEMBL4206967)
Affinity DataIC50: 790nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459687(CHEMBL4211498)
Affinity DataIC50: 820nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459705(CHEMBL4218467)
Affinity DataIC50: 880nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459703(CHEMBL4210297)
Affinity DataIC50: 940nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459666(CHEMBL4205404)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459689(CHEMBL4206755)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459696(CHEMBL4216261)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459683(CHEMBL2181277)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459674(CHEMBL4218959 | US12006283, Example 9)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459668(CHEMBL4210695)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459669(CHEMBL4212667 | US12006283, Example 7)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459670(CHEMBL4218636)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459698(CHEMBL4214799 | US12006283, Example 13)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459690(CHEMBL2177146)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459700(CHEMBL4202536)
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459673(CHEMBL4212009)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459675(CHEMBL4212353 | US12006283, Example 11)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459688(CHEMBL4209652)
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459680(CHEMBL4218093)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459701(CHEMBL4213708)
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459704(CHEMBL4204784)
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459692(CHEMBL4213537)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459679(CHEMBL4214222)
Affinity DataIC50: 5.25E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459691(CHEMBL4215663 | US12006283, Example 16)
Affinity DataIC50: 5.28E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459686(CHEMBL4215277)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459682(CHEMBL4218167)
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459665(CHEMBL4202804 | US12006283, Example 15)
Affinity DataIC50: 6.52E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459672(CHEMBL4208298 | US12006283, Example 12)
Affinity DataIC50: 6.85E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459671(CHEMBL4203146 | US12006283, Example 14)
Affinity DataIC50: 7.35E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459702(CHEMBL4210709)
Affinity DataIC50: 8.45E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459693(CHEMBL4215953 | US12006283, Example 8)
Affinity DataIC50: 8.74E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459681(CHEMBL4206380)
Affinity DataIC50: 8.88E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459678(CHEMBL4209306)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459667(CHEMBL4215392)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459695(CHEMBL4215664)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459677(CHEMBL4217535)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459694(CHEMBL4213782)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459676(CHEMBL4216129 | US12006283, Example 5)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed