Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50007139
TargetTyrosine-protein kinase BTK(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357312BDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 23nMAssay Description:Inhibition of CDK5/p35 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 24nMAssay Description:Inhibition of CDK2/CyclinE (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50309910BDBM50309910(N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...)
Affinity DataIC50: 465nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 911nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 12(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPK14 (unknown origin) after 22 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin) after 22 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506700BDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed