Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50003184
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467971BDBM50467971(CHEMBL4290245)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467973BDBM50467973(CHEMBL4287193)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467978BDBM50467978(CHEMBL4282729)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148831BDBM50148831(CHEMBL3770342)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467970BDBM50467970(CHEMBL4293638)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467977BDBM50467977(CHEMBL4290607)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467968BDBM50467968(CHEMBL1373650)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467971BDBM50467971(CHEMBL4290245)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at 5HT2B (unknown origin) expressed in CHOK1 cells assessed as inhibition of agonist-induced effect preincubated for 60 mins at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 112780BDBM112780(US8629135, SW-07)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148831BDBM50148831(CHEMBL3770342)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at 5HT2B (unknown origin) expressed in CHOK1 cells assessed as inhibition of agonist-induced effect preincubated for 60 mins at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467970BDBM50467970(CHEMBL4293638)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at 5HT2B (unknown origin) expressed in CHOK1 cells assessed as inhibition of agonist-induced effect preincubated for 60 mins at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467972BDBM50467972(CHEMBL4286420)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467975BDBM50467975(CHEMBL4292168)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at 5HT2B (unknown origin) expressed in CHOK1 cells assessed as inhibition of agonist-induced effect preincubated for 60 mins at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467969BDBM50467969(CHEMBL3770837)
Affinity DataKi:  151nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467974BDBM50467974(CHEMBL4294723)
Affinity DataIC50: 215nMAssay Description:Antagonist activity at 5HT2B (unknown origin) expressed in CHOK1 cells assessed as inhibition of agonist-induced effect preincubated for 60 mins at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467967BDBM50467967(CHEMBL4286819)
Affinity DataKi:  314nMAssay Description:Displacement of [3H]LSD from 5HT2B (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467972BDBM50467972(CHEMBL4286420)
Affinity DataIC50: 403nMAssay Description:Antagonist activity at 5HT2B (unknown origin) expressed in CHOK1 cells assessed as inhibition of agonist-induced effect preincubated for 60 mins at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467968BDBM50467968(CHEMBL1373650)
Affinity DataIC50: 459nMAssay Description:Antagonist activity at 5HT2B (unknown origin) expressed in CHOK1 cells assessed as inhibition of agonist-induced effect preincubated for 60 mins at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467969BDBM50467969(CHEMBL3770837)
Affinity DataIC50: 1.64E+3nMAssay Description:Antagonist activity at 5HT2B (unknown origin) expressed in CHOK1 cells assessed as inhibition of agonist-induced effect preincubated for 60 mins at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467976BDBM50467976(CHEMBL4281546)
Affinity DataIC50: 1.96E+3nMAssay Description:Antagonist activity at 5HT2B (unknown origin) expressed in CHOK1 cells assessed as inhibition of agonist-induced effect preincubated for 60 mins at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed