Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50008642
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521039BDBM50521039(CHEMBL4449681)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of recombinant human wild type GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system after 1 hr by kinase trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5447BDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of recombinant human wild type GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system after 1 hr by kinase trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521051BDBM50521051(CHEMBL4439974)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of recombinant human wild type GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system after 1 hr by kinase trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521047BDBM50521047(CHEMBL4530170)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of recombinant human wild type GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system after 1 hr by kinase trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521041BDBM50521041(CHEMBL4562352)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521052BDBM50521052(CHEMBL4526992)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of recombinant human wild type GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system after 1 hr by kinase trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521048BDBM50521048(CHEMBL4440618)
Affinity DataIC50: 0.870nMAssay Description:Inhibition of recombinant human wild type GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system after 1 hr by kinase trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521047BDBM50521047(CHEMBL4530170)
Affinity DataIC50: 5nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521048BDBM50521048(CHEMBL4440618)
Affinity DataIC50: 7nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521050BDBM50521050(CHEMBL4572315)
Affinity DataIC50: 11nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521043BDBM50521043(CHEMBL4556799)
Affinity DataIC50: 12nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521042BDBM50521042(CHEMBL4530987)
Affinity DataIC50: 14nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521040BDBM50521040(CHEMBL4435699)
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521046BDBM50521046(CHEMBL4437599)
Affinity DataIC50: 25nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521037BDBM50521037(CHEMBL4558356)
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521039BDBM50521039(CHEMBL4449681)
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521052BDBM50521052(CHEMBL4526992)
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521051BDBM50521051(CHEMBL4439974)
Affinity DataIC50: 34nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521038BDBM50521038(CHEMBL4538707)
Affinity DataIC50: 44nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5447BDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 60nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521049BDBM50521049(CHEMBL4521214)
Affinity DataIC50: 70nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521044BDBM50521044(CHEMBL4473375)
Affinity DataIC50: 83nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521045BDBM50521045(CHEMBL4559217)
Affinity DataIC50: 197nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed