Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50008972
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2483BDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137113BDBM50137113(CHEMBL3753096)
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137112BDBM50137112(CHEMBL309896)
Affinity DataIC50: 12nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3107BDBM3107(6-chloro-4-cyclopropyl-4-[2-(pyridin-2-yl)ethynyl]...)
Affinity DataIC50: 23nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1517BDBM1517(CHEMBL37628 | 2-ethyl-7-methyl-2,4,9,15-tetraazatr...)
Affinity DataIC50: 35nMAssay Description:Inhibition of HIV1 reverse transcriptase derived from HIV patient plasma by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2483BDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 38nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524092BDBM50524092(CHEMBL4436313)
Affinity DataIC50: 46nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524088BDBM50524088(CHEMBL4483481)
Affinity DataIC50: 56nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524089BDBM50524089(CHEMBL4529500)
Affinity DataIC50: 82nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1434BDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 84nMAssay Description:Inhibition of HIV1 reverse transcriptase derived from HIV patient plasma by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1518BDBM1518(CHEMBL37343 | 2-ethyl-9-methyl-2,4,9,15-tetraazatr...)
Affinity DataIC50: 125nMAssay Description:Inhibition of HIV1 reverse transcriptase derived from HIV patient plasma by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1944BDBM1944(BHAP deriv. | N-[2-({4-[3-(propan-2-ylamino)pyridi...)
Affinity DataIC50: 260nMAssay Description:Inhibition of wild type recombinant HIV1 reverse transcriptase using poly(rA)-oligo(dT) as template/primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1633BDBM1633(2-ethyl-10-methyl-2,4,10-triazatricyclo[9.4.0.0^{3...)
Affinity DataIC50: 350nMAssay Description:Inhibition of HIV1 reverse transcriptase derived from HIV patient plasma by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137120BDBM50137120(CHEMBL3753006)
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137115BDBM50137115(CHEMBL3754170)
Affinity DataIC50: 950nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1437BDBM1437(BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of wild type recombinant HIV1 reverse transcriptase using poly(rA)-oligo(dT) as template/primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524091BDBM50524091(CHEMBL307792)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase derived from HIV patient plasma by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1944BDBM1944(BHAP deriv. | N-[2-({4-[3-(propan-2-ylamino)pyridi...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of wild type recombinant HIV1 reverse transcriptase Y181C mutant using poly(rA)-oligo(dT) as template/primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524093BDBM50524093(CHEMBL311050)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524090BDBM50524090(CHEMBL1192060)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of wild type recombinant HIV1 reverse transcriptase using poly(rA)-oligo(dT) as template/primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed