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Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50011531 Sort by
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to human CSE by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to human CSE by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate in presence of 0.025% Triton X-100 by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate in presence of 0.01% Triton X-100 by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human CSE by methylene blue methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine beta-synthase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CBS (unknown origin) by AzMC based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by LC/MS/MS-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by LC/MS/MS-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50: 6.20E+3nMAssay Description:Non-covalent reversible inhibition of human CSEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by LC/MS/MS-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine beta-synthase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CBS (unknown origin) by methylene blue methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibition of wild type human CSE expressed in HEK293T cells assessed as reduction in H2S contentsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Mouse)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibition of CSE in mouse RAW264.7 cells assessed as reduction in endogenous H2S level by AzMC probe based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548268(CHEMBL4759091)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548273(CHEMBL4740853)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM25469(2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]-1-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50235883(CHEMBL1702248)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM114207(SMR001797995 | MLS002920403 | Kalafungin | cid_283...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548272(CHEMBL4741600)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM80755(cid_266923 | SMR001565537 | 6-azanyl-7-bromanyl-qu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548271(CHEMBL1098773)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50447761(CHEMBL60908)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548270(CHEMBL4749230)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM80987(MLS002608219 | cid_237102 | 2-chloro-3-(4-methylpi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548269(CHEMBL1981644)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548274(CHEMBL1978705)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548275(CHEMBL2001273)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548276(CHEMBL4790519)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548277(CHEMBL4787936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine beta-synthase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 5.42E+4nMAssay Description:Inhibition of human CBS by methylene blue methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548279(CHEMBL4784652)
Affinity DataIC50: 5.99E+4nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548280(CHEMBL1205573)
Affinity DataIC50: 1.43E+5nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548281(CHEMBL4781645)
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548283(Olsalazine | C. i. mordant yellow 5 | Dipentum | U...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548282(CHEMBL4743182)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM26193(salicylic acid | 2-Hydroxybenzoate, I | CHEMBL424 ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60918(5-Amino-2-hydroxy-benzoic acid | cid_4075 | MLS001...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548278(CHEMBL4748507)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 2.45E+5nMAssay Description:Inhibition of human CSE R119K mutant expressed in HEK293T cells assessed as reduction in H2S contentsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 2.83E+5nMAssay Description:Inhibition of human CSE Y114F mutant expressed in HEK293T cells assessed as reduction in H2S contentsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 3.71E+5nMAssay Description:Inhibition of human CSE R119A mutant expressed in HEK293T cells assessed as reduction in H2S contentsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Mouse)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM367671(US10227314, Compound 2-aminopent-4-ynoic acid)
Affinity DataIC50: 3.71E+5nMAssay Description:Inhibition of CSE in mouse RAW264.7 cells assessed as reduction in endogenous H2S level by AzMC probe based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine beta-synthase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 6.50E+5nMAssay Description:Inhibition of wild type human CBS expressed in HEK293T cells assessed as reduction in H2S contentsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataKi:  600nMAssay Description:Competitive inhibition of human CSE using varying levels of L-Cys as substrate and fixed PLP levelsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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