Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50007219 Sort by
TargetCytochrome P450 1A2(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50507479(CHEMBL4447260)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 1B1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108048(2-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-thiophene |...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1B1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50507479(CHEMBL4447260)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 1B1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108052(trans-2,4,3',5'-tetramethoxystilbene | 1-[(E)-2-(3...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108048(2-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-thiophene |...)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1B1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1A1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50507479(CHEMBL4447260)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 1A1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1A1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108048(2-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-thiophene |...)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1A1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108052(trans-2,4,3',5'-tetramethoxystilbene | 1-[(E)-2-(3...)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108052(trans-2,4,3',5'-tetramethoxystilbene | 1-[(E)-2-(3...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed