Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50007309 Sort by
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508416(CHEMBL4518815)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508415(CHEMBL4459798)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508413(CHEMBL4459166)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508413(CHEMBL4459166)
Affinity DataIC50: 70nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM371331(US10239843, Example 438 | 1-Ethyl-N-[1-(fluorometh...)
Affinity DataIC50: 80nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM371184(US10239843, Example 291)
Affinity DataIC50: 80nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508416(CHEMBL4518815)
Affinity DataIC50: 90nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM371331(US10239843, Example 438 | 1-Ethyl-N-[1-(fluorometh...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508415(CHEMBL4459798)
Affinity DataIC50: 170nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM371184(US10239843, Example 291)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM371301(US10239843, Example 408 | N-[1-(Fluoromethyl)cyclo...)
Affinity DataIC50: 290nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508414(CHEMBL4456850)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM371048(US10239843, Example 155 | US10239843, Example 489)
Affinity DataIC50: 330nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM371048(US10239843, Example 155 | US10239843, Example 489)
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM371301(US10239843, Example 408 | N-[1-(Fluoromethyl)cyclo...)
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508414(CHEMBL4456850)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508418(CHEMBL4555002)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508417(CHEMBL4451386)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508417(CHEMBL4451386)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508418(CHEMBL4555002)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed