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Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50010112
TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50315700(CHEMBL4161975)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535263(CHEMBL4456149)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50315702(CHEMBL4166126)
Affinity DataIC50:  270nMAssay Description:Inhibition of HO-1 in rat spleen microsomes incubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50315702(CHEMBL4166126)
Affinity DataIC50:  460nMAssay Description:Inhibition of HO-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535261(CHEMBL4541767)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50207199(1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)m...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50271549(1-(4-(3-bromophenoxy)butyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50271549(1-(4-(3-bromophenoxy)butyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of HO-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM84805(1-azolyl-4-phenyl-2-butanone, 7)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535258(CHEMBL2298629)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535262(CHEMBL4474542)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant truncated HO-1 (Met1 to Pro267) in rat spleen microsomes expressed in Escherichia coli by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50252801(1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone hy...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of HO-1 in rat spleen microsomes incubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526843(CHEMBL4540989)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535262(CHEMBL4474542)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526845(CHEMBL4454118)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526846(CHEMBL4559629)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526848(CHEMBL4448858)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526847(CHEMBL4464730)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535266(CHEMBL4589369)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50271514(1-(6-(4-bromophenoxy)hexyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535265(CHEMBL1190440)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM84805(1-azolyl-4-phenyl-2-butanone, 7)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50025988(1-(2-Phenoxy-ethyl)-1H-imidazole | CHEMBL284827)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535259(CHEMBL4534531)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535257(CHEMBL4448183)
Affinity DataIC50:  3.01E+4nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535256(CHEMBL4552455)
Affinity DataIC50:  3.19E+4nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526843(CHEMBL4540989)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535255(CHEMBL4442308)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535264(CHEMBL4459358)
Affinity DataIC50:  6.76E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535260(CHEMBL4538246)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50207199(1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HO-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526848(CHEMBL4448858)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50252801(1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone hy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HO-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526846(CHEMBL4559629)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526845(CHEMBL4454118)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526847(CHEMBL4464730)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535257(CHEMBL4448183)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50535256(CHEMBL4552455)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant truncated HO-2 (Met1 to Ala288) in rat brain microsomes expressed in Escherichia coli by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed