Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50010112
TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315700BDBM50315700(CHEMBL4161975)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535263BDBM50535263(CHEMBL4456149)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315702BDBM50315702(CHEMBL4166126)
Affinity DataIC50: 270nMAssay Description:Inhibition of HO-1 in rat spleen microsomes incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315702BDBM50315702(CHEMBL4166126)
Affinity DataIC50: 460nMAssay Description:Inhibition of HO-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535261BDBM50535261(CHEMBL4541767)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50207199BDBM50207199(1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)m...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271549BDBM50271549(1-(4-(3-bromophenoxy)butyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271549BDBM50271549(1-(4-(3-bromophenoxy)butyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of HO-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 84805BDBM84805(1-azolyl-4-phenyl-2-butanone, 7)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535258BDBM50535258(CHEMBL2298629)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535262BDBM50535262(CHEMBL4474542)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183062BDBM50183062(CHEMBL541899 | CHEMBL495072 | 1-((2-(4-chlorophene...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant truncated HO-1 (Met1 to Pro267) in rat spleen microsomes expressed in Escherichia coli by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252801BDBM50252801(1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone hy...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HO-1 in rat spleen microsomes incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526843BDBM50526843(CHEMBL4540989)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535262BDBM50535262(CHEMBL4474542)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526845BDBM50526845(CHEMBL4454118)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526846BDBM50526846(CHEMBL4559629)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526848BDBM50526848(CHEMBL4448858)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526847BDBM50526847(CHEMBL4464730)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535266BDBM50535266(CHEMBL4589369)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271514BDBM50271514(1-(6-(4-bromophenoxy)hexyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535265BDBM50535265(CHEMBL1190440)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 84805BDBM84805(1-azolyl-4-phenyl-2-butanone, 7)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025988BDBM50025988(1-(2-Phenoxy-ethyl)-1H-imidazole | CHEMBL284827)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535259BDBM50535259(CHEMBL4534531)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535257BDBM50535257(CHEMBL4448183)
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535256BDBM50535256(CHEMBL4552455)
Affinity DataIC50: 3.19E+4nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526843BDBM50526843(CHEMBL4540989)
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535255BDBM50535255(CHEMBL4442308)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human recombinant HO-1 by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535264BDBM50535264(CHEMBL4459358)
Affinity DataIC50: 6.76E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535260BDBM50535260(CHEMBL4538246)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526845BDBM50526845(CHEMBL4454118)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526847BDBM50526847(CHEMBL4464730)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535257BDBM50535257(CHEMBL4448183)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535256BDBM50535256(CHEMBL4552455)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252801BDBM50252801(1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone hy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50207199BDBM50207199(1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526848BDBM50526848(CHEMBL4448858)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183062BDBM50183062(CHEMBL541899 | CHEMBL495072 | 1-((2-(4-chlorophene...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant truncated HO-2 (Met1 to Ala288) in rat brain microsomes expressed in Escherichia coli by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526846BDBM50526846(CHEMBL4559629)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed