Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50007712 Sort by
TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50511979(Cethromycin)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50511980(CHEMBL4459487)
Affinity DataIC50: 5.14E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50511978(CHEMBL4537107)
Affinity DataIC50: 7.32E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378137(Ketek | TELITHROMYCIN)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50511981(CHEMBL4466824)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed