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Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50007712
TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataIC50:  60nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50511979(Cethromycin)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50511980(CHEMBL4459487)
Affinity DataIC50:  5.14E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50511978(CHEMBL4537107)
Affinity DataIC50:  7.32E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50378137(Ketek | TELITHROMYCIN)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50511981(CHEMBL4466824)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in metabolite formation using midazolam as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed