Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50008939
LigandChemical structure of BindingDB Monomer ID 50523773BDBM50523773(CHEMBL4475999)
Affinity DataIC50: 60nMAssay Description:Inhibition of Kv1.5 in human atrial myocytes assessed as blockade of Ikur currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50392995BDBM50392995(CHEMBL2152523)
Affinity DataIC50: 130nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523766BDBM50523766(CHEMBL4476275)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523770BDBM50523770(CHEMBL4451245)
Affinity DataIC50: 260nMAssay Description:Inhibition of Kv1.5 in human atrial myocytes assessed as blockade of Ikur currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523771BDBM50523771(CHEMBL4527638)
Affinity DataIC50: 390nMAssay Description:Inhibition of Kv1.5 in human atrial myocytes assessed as blockade of Ikur currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50392995BDBM50392995(CHEMBL2152523)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523772BDBM50523772(CHEMBL4533149)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50392995BDBM50392995(CHEMBL2152523)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523773BDBM50523773(CHEMBL4475999)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523774BDBM50523774(CHEMBL4517112)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523763BDBM50523763(CHEMBL4438854)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523775BDBM50523775(CHEMBL4453132)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523765BDBM50523765(CHEMBL4437013)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523768BDBM50523768(CHEMBL4539540)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523773BDBM50523773(CHEMBL4475999)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Kir3.1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523773BDBM50523773(CHEMBL4475999)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Kir3.4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523771BDBM50523771(CHEMBL4527638)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523764BDBM50523764(CHEMBL4468664)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50523765BDBM50523765(CHEMBL4437013)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523767BDBM50523767(CHEMBL4474540)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523766BDBM50523766(CHEMBL4476275)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523770BDBM50523770(CHEMBL4451245)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523769BDBM50523769(CHEMBL4466634)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523773BDBM50523773(CHEMBL4475999)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523763BDBM50523763(CHEMBL4438854)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50523773BDBM50523773(CHEMBL4475999)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50523766BDBM50523766(CHEMBL4476275)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50523763BDBM50523763(CHEMBL4438854)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523765BDBM50523765(CHEMBL4437013)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523766BDBM50523766(CHEMBL4476275)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523763BDBM50523763(CHEMBL4438854)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523773BDBM50523773(CHEMBL4475999)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523773BDBM50523773(CHEMBL4475999)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523773BDBM50523773(CHEMBL4475999)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of CaV1.2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50392995BDBM50392995(CHEMBL2152523)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50523765BDBM50523765(CHEMBL4437013)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed