Found 73 Enz. Inhib. hit(s) with all data for entry = 50008705 
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]-DAMGO from mu-type opioid receptor in guinea pig brain membranes preincubated for 15 mins followed by [3H]-DAMGO addition and me...More data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by liquid scintillation cou...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 68nMAssay Description:Displacement of [3H]-U69593 from kappa-type opioid receptor in guinea pig brain membranes preincubated for 15 mins followed by [3H]-U69593 addition a...More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 108nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 171nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 175nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 201nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 307nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 319nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 360nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 387nMAssay Description:Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 408nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 528nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 575nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scint...More data for this Ligand-Target Pair
