Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50007743
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512182(CHEMBL4454117)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512207(CHEMBL4471194)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512206(CHEMBL4558064)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512215(CHEMBL4550067)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512210(CHEMBL4541775)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512187(CHEMBL4449682)
Affinity DataIC50: 3.48E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512192(CHEMBL4466968)
Affinity DataIC50: 3.59E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512209(CHEMBL4461990)
Affinity DataIC50: 4.37E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512217(CHEMBL4452830)
Affinity DataIC50: 5.77E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512181(CHEMBL4441534)
Affinity DataIC50: 5.83E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512201(CHEMBL4583424)
Affinity DataIC50: 5.86E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512200(CHEMBL4576223)
Affinity DataIC50: 6.09E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512219(CHEMBL4563493)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512203(CHEMBL4450448)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512191(CHEMBL4573966)
Affinity DataIC50: 6.12E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512205(CHEMBL4530821)
Affinity DataIC50: 6.36E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512213(CHEMBL4526574)
Affinity DataIC50: 6.36E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512198(CHEMBL4588268)
Affinity DataIC50: 6.96E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512208(CHEMBL4585556)
Affinity DataIC50: 7.14E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512202(CHEMBL4474303)
Affinity DataIC50: 7.28E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512212(CHEMBL4465188)
Affinity DataIC50: 8.21E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512196(CHEMBL4457484)
Affinity DataIC50: 8.83E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512194(CHEMBL4438223)
Affinity DataIC50: 9.16E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512188(CHEMBL4472953)
Affinity DataIC50: 9.22E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512218(CHEMBL4459938)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512184(CHEMBL4452559)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512183(CHEMBL4466015)
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512206(CHEMBL4558064)
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of human topoisomerase 2 by decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512211(CHEMBL4437494)
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512209(CHEMBL4461990)
Affinity DataIC50: 1.65E+5nMAssay Description:Inhibition of human topoisomerase 2 by decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512189(CHEMBL4457241)
Affinity DataIC50: 1.68E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512197(CHEMBL4473096)
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512221(CHEMBL4563179)
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512193(CHEMBL4437980)
Affinity DataIC50: 1.84E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512214(CHEMBL4514473)
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512224(CHEMBL4436014)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512195(CHEMBL4564901)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512222(CHEMBL4475343)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512223(CHEMBL4472165)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512190(CHEMBL4530742)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512220(CHEMBL4525971)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512204(CHEMBL4563149)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512186(CHEMBL4551923)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512185(CHEMBL4461347)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512216(CHEMBL4453816)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512199(CHEMBL4515633)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed