Compile Data Set for Download or QSAR
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Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50035691
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  25nMAssay Description:Inhibition of dihydrofolate reductase(DHFR) from L1210/R81 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50022332(5-(2-Chloro-acetylamino)-2-{4-[(2,4-diamino-pterid...)
Affinity DataIC50:  32nMAssay Description:Inhibition of dihydrofolate reductase(DHFR) from L1210/R81 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50022329(6-(2-Chloro-acetylamino)-2-{4-[(2,4-diamino-pterid...)
Affinity DataIC50:  32nMAssay Description:Inhibition of dihydrofolate reductase(DHFR) from L1210/R81 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50022330(5-(2-Bromo-acetylamino)-2-{4-[(2,4-diamino-pteridi...)
Affinity DataIC50:  46nMAssay Description:Inhibition of dihydrofolate reductase(DHFR) from L1210/R81 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50022331(6-(2-Bromo-acetylamino)-2-{4-[(2,4-diamino-pteridi...)
Affinity DataIC50:  72nMAssay Description:Inhibition of dihydrofolate reductase(DHFR) from L1210/R81 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed