Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50035653
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022353BDBM50022353({1-[1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 2nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022370BDBM50022370({1-[1-(3-Cyclohexanesulfonyl-1-cyclohexylmethyl-2-...)
Affinity DataIC50: 2.5nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226408BDBM50226408(CHEMBL3142220)
Affinity DataIC50: 3nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022379BDBM50022379([1-[1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 3nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022350BDBM50022350(N-{1-[1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2...)
Affinity DataIC50: 3.5nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022376BDBM50022376((1-{1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 4nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022372BDBM50022372({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-isopropylsul...)
Affinity DataIC50: 4nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022356BDBM50022356({1-[1-(1-Cyclohexylmethyl-3-cyclohexylsulfanyl-2-h...)
Affinity DataIC50: 4nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022381BDBM50022381({1-[1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 5nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022364BDBM50022364({2-Benzyloxy-1-[1-[1-cyclohexylmethyl-2-hydroxy-3-...)
Affinity DataIC50: 5.5nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022373BDBM50022373((1-{2-Benzyloxy-1-[1-cyclohexylmethyl-2-hydroxy-3-...)
Affinity DataIC50: 6nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022382BDBM50022382({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-isobutylsulf...)
Affinity DataIC50: 6.5nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022368BDBM50022368((1-{1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 8nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022375BDBM50022375({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-isopropylsul...)
Affinity DataIC50: 9.90nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022359BDBM50022359(3-Benzyloxy-N-[1-[1-cyclohexylmethyl-2-hydroxy-3-(...)
Affinity DataIC50: 10nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022358BDBM50022358({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-methylsulfan...)
Affinity DataIC50: 10nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022383BDBM50022383({1-[1-(1-Benzyl-3-cyclohexylsulfanyl-2-hydroxy-pro...)
Affinity DataIC50: 15nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022362BDBM50022362((1-{1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 20nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022371BDBM50022371({2-Benzyloxy-1-[1-[1-cyclohexylmethyl-2-hydroxy-3-...)
Affinity DataIC50: 20nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022354BDBM50022354(2-Benzyl-N-[1-(1-cyclohexylmethyl-3-cyclohexylsulf...)
Affinity DataIC50: 20nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022369BDBM50022369(2-(2-Benzyl-3-phenyl-propionylamino)-4-methyl-pent...)
Affinity DataIC50: 25nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022378BDBM50022378((1-{1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 30nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022377BDBM50022377({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-methanesulfo...)
Affinity DataIC50: 40nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022352BDBM50022352((1-{1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 40nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022363BDBM50022363(2-Benzyl-N-[1-(3-cyclohexanesulfonyl-1-cyclohexylm...)
Affinity DataIC50: 40nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022366BDBM50022366({4-(2-tert-Butoxycarbonylamino-3-phenyl-propionyla...)
Affinity DataIC50: 60nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022357BDBM50022357((1-{1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 70nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022365BDBM50022365(2-Benzyl-N-[1-[1-cyclohexylmethyl-2-hydroxy-3-(pro...)
Affinity DataIC50: 70nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022374BDBM50022374({2-Benzyloxy-1-[1-[1-cyclohexylmethyl-2-hydroxy-3-...)
Affinity DataIC50: 75nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022351BDBM50022351({1-[1-(1-Cyclohexylmethyl-3-cyclohexylsulfanyl-2-h...)
Affinity DataIC50: 100nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022380BDBM50022380({5-(2-tert-Butoxycarbonylamino-3-phenyl-propionyla...)
Affinity DataIC50: 100nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022367BDBM50022367({1-[1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 150nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022360BDBM50022360(2-Amino-3-benzyloxy-N-[1-[1-cyclohexylmethyl-2-hyd...)
Affinity DataIC50: 300nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022355BDBM50022355((1-{5-Acetylamino-1-[1-cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50: 300nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022361BDBM50022361(N-(1-Cyclohexylmethyl-3-cyclohexylsulfanyl-2-hydro...)
Affinity DataIC50: 430nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed