Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50007376
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508934(CHEMBL4463817)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508933(CHEMBL4461511)
Affinity DataIC50: 960nMAssay Description:Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508934(CHEMBL4463817)
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508933(CHEMBL4461511)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508934(CHEMBL4463817)
Affinity DataIC50: 2.70E+4nMAssay Description:Antagonist activity at human AChR alpha7 transfected in rat GH3 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508933(CHEMBL4461511)
Affinity DataIC50: 4.53E+4nMAssay Description:Antagonist activity at human AChR alpha7 transfected in rat GH3 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508935(CHEMBL4474412)
Affinity DataIC50: 1.45E+5nMAssay Description:Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508935(CHEMBL4474412)
Affinity DataIC50: 1.67E+5nMAssay Description:Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed