Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50008077
TargetB2 bradykinin receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50142954BDBM50142954(4-[(E)-2-({1-[2,4-Dichloro-3-(4-imidazol-1-yl-2-me...)
Affinity DataIC50: 0.260nMAssay Description:Displacement of [3H]bradykinin from human recombinant bradykinin B2 receptor expressed in CHO cells incubated for 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Guinea pig)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067290BDBM50067290(5-{2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxy...)
Affinity DataIC50: 0.460nMAssay Description:Displacement of [3H]BK from Bradykinin B2 Receptor in guinea pig ileum by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515483BDBM50515483(CHEMBL4466350)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of VEGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515481BDBM50515481(CHEMBL4439680)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of VEGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515483BDBM50515483(CHEMBL4466350)
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515481BDBM50515481(CHEMBL4439680)
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetP-selectin(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100507BDBM50100507(3-(4-{4-[4-(2-Carboxy-vinyl)-phenyl]-5-[4-(2-hexad...)
Affinity DataIC50: 300nMAssay Description:Inhibition of P-selectin (unknown origin) incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515482BDBM50515482(CHEMBL4453659)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341135BDBM50341135(N-p-Coumaroyl serotonin | CHEMBL1760547)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of recombinant human MAOB using kynuramine as substrate preincubated with substrate for 10 mins followed by enzyme addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50429762BDBM50429762(N-(2-Methoxyphenyl)Cinnamamide | CHEMBL2336355)
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of recombinant His-tagged human EGFR (645 to 1186 residues) cytoplasmic domain expressed in baculovirus infected Sf9 cells incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50429757BDBM50429757(N-(2-Fluorophenyl)Cinnamamide | CHEMBL1998736)
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of recombinant His-tagged human EGFR (645 to 1186 residues) cytoplasmic domain expressed in baculovirus infected Sf9 cells incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetP-selectin(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100506BDBM50100506(3-(4-{5-[4-(2-Hexadecylcarbamoyl-vinyl)-phenyl]-1H...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of P-selectin (unknown origin) incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515484BDBM50515484(CHEMBL4588220)
Affinity DataIC50: 8.67E+4nMAssay Description:Inhibition of recombinant human BACE 1 using Rh-EVNL-DAEFK-Quencher as substrate incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed