Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50009039
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524812BDBM50524812(CHEMBL4468186)
Affinity DataIC50: 21nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277889BDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 24nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524799BDBM50524799(CHEMBL4454410)
Affinity DataIC50: 26nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524792BDBM50524792(CHEMBL4475249)
Affinity DataIC50: 27nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524795BDBM50524795(CHEMBL4439181)
Affinity DataIC50: 31nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524806BDBM50524806(CHEMBL4451933)
Affinity DataIC50: 31nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524807BDBM50524807(CHEMBL4438000)
Affinity DataIC50: 32nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524796BDBM50524796(CHEMBL4577122)
Affinity DataIC50: 34nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524811BDBM50524811(CHEMBL4589171)
Affinity DataIC50: 37nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524797BDBM50524797(CHEMBL4541035)
Affinity DataIC50: 37nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524789BDBM50524789(CHEMBL4517455)
Affinity DataIC50: 37nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524793BDBM50524793(CHEMBL4582067)
Affinity DataIC50: 38nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524801BDBM50524801(CHEMBL4474079)
Affinity DataIC50: 39nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524813BDBM50524813(CHEMBL4437784)
Affinity DataIC50: 42nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524800BDBM50524800(CHEMBL4543154)
Affinity DataIC50: 43nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524805BDBM50524805(CHEMBL4579185)
Affinity DataIC50: 45nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524814BDBM50524814(CHEMBL4437781)
Affinity DataIC50: 48nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524794BDBM50524794(CHEMBL4591459)
Affinity DataIC50: 51nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524808BDBM50524808(CHEMBL4476793)
Affinity DataIC50: 52nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524791BDBM50524791(CHEMBL4566822)
Affinity DataIC50: 52nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524790BDBM50524790(CHEMBL4470410)
Affinity DataIC50: 57nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524798BDBM50524798(CHEMBL4546157)
Affinity DataIC50: 61nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524802BDBM50524802(CHEMBL4513562)
Affinity DataIC50: 65nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524809BDBM50524809(CHEMBL4468592)
Affinity DataIC50: 77nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524803BDBM50524803(CHEMBL4533623)
Affinity DataIC50: 98nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524788BDBM50524788(CHEMBL4517879)
Affinity DataIC50: 140nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524810BDBM50524810(CHEMBL4527204)
Affinity DataIC50: 162nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524804BDBM50524804(CHEMBL4460843)
Affinity DataIC50: 729nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277889BDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 9.21E+4nMAssay Description:Inhibition of human ERG in HEK293 cells assessed as effect on QT intervalMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed