Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50007811
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512828BDBM50512828(CHEMBL4461112)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512817BDBM50512817(CHEMBL4476232)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161162BDBM50161162(AVL-292 | CC-292 | Spebrutinib | US9987276, Compou...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512851BDBM50512851(CHEMBL4437107)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512850BDBM50512850(CHEMBL4470534)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357312BDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512846BDBM50512846(CHEMBL4434879)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512826BDBM50512826(CHEMBL4583844)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512838BDBM50512838(CHEMBL4464989)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512835BDBM50512835(CHEMBL4473373)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512814BDBM50512814(CHEMBL4466032)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512840BDBM50512840(CHEMBL4590126)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512837BDBM50512837(CHEMBL4521840)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512831BDBM50512831(CHEMBL4517522)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512842BDBM50512842(CHEMBL4455814)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512833BDBM50512833(CHEMBL4449266)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512811BDBM50512811(CHEMBL4459604)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512829BDBM50512829(CHEMBL4435537)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512843BDBM50512843(CHEMBL4548939)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512834BDBM50512834(CHEMBL4435828)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512821BDBM50512821(CHEMBL4468913)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512820BDBM50512820(CHEMBL4462242)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512830BDBM50512830(CHEMBL4435060)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512832BDBM50512832(CHEMBL4443136)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512822BDBM50512822(CHEMBL4439745)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512827BDBM50512827(CHEMBL4551071)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512836BDBM50512836(CHEMBL4438747)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512848BDBM50512848(CHEMBL4437246)
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512845BDBM50512845(CHEMBL4445733)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512823BDBM50512823(CHEMBL4453432)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512844BDBM50512844(CHEMBL4537525)
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512816BDBM50512816(CHEMBL4540071)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512815BDBM50512815(CHEMBL4473486)
Affinity DataIC50: 98nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512839BDBM50512839(CHEMBL4460184)
Affinity DataIC50: 115nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512819BDBM50512819(CHEMBL4454876)
Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512841BDBM50512841(CHEMBL4447148)
Affinity DataIC50: 131nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512812BDBM50512812(CHEMBL4443744)
Affinity DataIC50: 155nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512818BDBM50512818(CHEMBL4476311)
Affinity DataIC50: 241nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512824BDBM50512824(CHEMBL4434679)
Affinity DataIC50: 264nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512813BDBM50512813(CHEMBL4576295)
Affinity DataIC50: 284nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512825BDBM50512825(CHEMBL4575729)
Affinity DataIC50: 386nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512849BDBM50512849(CHEMBL4591477)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512847BDBM50512847(CHEMBL4449314)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed