Compile Data Set for Download or QSAR
Report error Found 109 Enz. Inhib. hit(s) with all data for entry = 50009445
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528967BDBM50528967(CHEMBL4439415)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528966BDBM50528966(CHEMBL4521879)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528960BDBM50528960(CHEMBL4450250)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528965BDBM50528965(CHEMBL4550234)
Affinity DataEC50:  0.00177nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528967BDBM50528967(CHEMBL4439415)
Affinity DataKi:  0.0109nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528966BDBM50528966(CHEMBL4521879)
Affinity DataKi:  0.0109nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528965BDBM50528965(CHEMBL4550234)
Affinity DataKi:  0.0109nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528960BDBM50528960(CHEMBL4450250)
Affinity DataKi:  0.0109nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491417BDBM50491417(22-THIOCYANATOSALVINORIN A)
Affinity DataEC50:  0.0770nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528964BDBM50528964(CHEMBL4464797)
Affinity DataEC50:  0.190nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataIC50: 0.282nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 3(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325534BDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataEC50:  0.550nMAssay Description:Inhibition of ERK1 phosphorylation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325534BDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataEC50:  0.550nMAssay Description:Inhibition of ERK2 phosphorylation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491417BDBM50491417(22-THIOCYANATOSALVINORIN A)
Affinity DataKd:  0.590nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518036BDBM50518036(CHEMBL4467777 | US11484525, Compound BD-122LS-PZM2...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528969BDBM50528969(CHEMBL4458337)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528969BDBM50528969(CHEMBL4458337)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528969BDBM50528969(CHEMBL4458337)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528969BDBM50528969(CHEMBL4458337)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528969BDBM50528969(CHEMBL4458337)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528969BDBM50528969(CHEMBL4458337)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528968BDBM50528968(CHEMBL4577301)
Affinity DataEC50:  1.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528964BDBM50528964(CHEMBL4464797)
Affinity DataKd:  2.10nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000092BDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528979BDBM50528979(CHEMBL4544686)
Affinity DataEC50:  4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518036BDBM50518036(CHEMBL4467777 | US11484525, Compound BD-122LS-PZM2...)
Affinity DataEC50:  4.60nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528976BDBM50528976(CHEMBL4474914)
Affinity DataEC50:  4.60nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399881BDBM50399881(CHEMBL2180639)
Affinity DataEC50:  5nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325534BDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataEC50:  5.20nMAssay Description:Inhibition of p38 phosphorylation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474150BDBM50474150(CHEMBL58362)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474153BDBM50474153(CHEMBL61630)
Affinity DataKi:  7.20nMAssay Description:Inhibition of mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50474152BDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataKi:  13nMAssay Description:Inhibition of mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518022BDBM50518022(CHEMBL4458783)
Affinity DataEC50:  31nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399882BDBM50399882(CHEMBL2180638)
Affinity DataEC50:  37nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518026BDBM50518026(CHEMBL4449152)
Affinity DataKi:  42nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518036BDBM50518036(CHEMBL4467777 | US11484525, Compound BD-122LS-PZM2...)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528975BDBM50528975(CHEMBL4456635)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528972BDBM50528972(CHEMBL4577586)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528973BDBM50528973(CHEMBL4581231)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528972BDBM50528972(CHEMBL4577586)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528978BDBM50528978(CHEMBL4533745)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated beta arrestin 2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518036BDBM50518036(CHEMBL4467777 | US11484525, Compound BD-122LS-PZM2...)
Affinity DataEC50:  52nMAssay Description:Inhibition of mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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