Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50007617
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458532BDBM50458532(CHEMBL4216782)
Affinity DataKi:  0.470nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139355BDBM50139355(Dimethyl-[2-(6-phenyl-pyridin-2-ylsulfanyl)-ethyl]...)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004891BDBM50004891(CHEMBL2164327)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055575BDBM50055575(CHEMBL3321794)
Affinity DataKi:  0.700nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354493BDBM50354493(CHEMBL409662)
Affinity DataKi:  0.790nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510971BDBM50510971(CHEMBL4442472)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098551BDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150417BDBM50150417(N-[2-(4-Fluoro-phenoxy)-ethyl]-N''-[1-(4-fluoro-ph...)
Affinity DataKi:  2nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510970BDBM50510970(CHEMBL4521657)
Affinity DataKi:  2nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116963BDBM50116963(2a-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl...)
Affinity DataKi:  2.10nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458526BDBM50458526(CHEMBL4205349 | US20240199555, Reference E55888)
Affinity DataKi:  2.5nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50395192BDBM50395192(CHEMBL2164336)
Affinity DataKi:  2.60nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151310BDBM50151310(CHEMBL3302600)
Affinity DataKi:  3nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150405BDBM50150405(N-(2-Phenoxy-ethyl)-N''-(1-phenyl-ethyl)-[1,3,5]tr...)
Affinity DataKi:  3nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130279BDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.20nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510968BDBM50510968(CHEMBL4533865)
Affinity DataKi:  3.5nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 78940BDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510967BDBM50510967(CHEMBL3139441)
Affinity DataKi:  4.5nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30704BDBM30704(METERGOLINE | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458523BDBM50458523(JNJ-18038683)
Affinity DataKi:  6.5nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50220503BDBM50220503(CHEMBL348890)
Affinity DataKi:  7.20nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10755BDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210125BDBM50210125([2-(2',6'-dimethoxy-biphenyl-3-yl)-ethyl]-dimethyl...)
Affinity DataKi:  8.60nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510969BDBM50510969(CHEMBL4582321)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139355BDBM50139355(Dimethyl-[2-(6-phenyl-pyridin-2-ylsulfanyl)-ethyl]...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130269BDBM50130269(LSD,2-Bromo | (6aR,9R)-5-Bromo-7-methyl-4,6,6a,7,8...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098550BDBM50098550(SB-258719 | CHEMBL12264 | 3,N-Dimethyl-N-[1-methyl...)
Affinity DataKi:  32nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50154705BDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataKi:  37nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469883BDBM50469883(CHEBI:584020 | Deseril | Methysergide)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004891BDBM50004891(CHEMBL2164327)
Affinity DataKi:  90nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150417BDBM50150417(N-[2-(4-Fluoro-phenoxy)-ethyl]-N''-[1-(4-fluoro-ph...)
Affinity DataKi: >100nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150405BDBM50150405(N-(2-Phenoxy-ethyl)-N''-(1-phenyl-ethyl)-[1,3,5]tr...)
Affinity DataKi: >100nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21397BDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151310BDBM50151310(CHEMBL3302600)
Affinity DataKi:  121nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017721BDBM50017721(5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclop...)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510968BDBM50510968(CHEMBL4533865)
Affinity DataKi:  128nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024210BDBM50024210(1H-indole-3-ethanamine | CHEMBL6640 | 2-(3-indolyl...)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116963BDBM50116963(2a-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl...)
Affinity DataKi:  169nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50154705BDBM50154705(4-Methoxy-N-{3-[4-(o-methoxyphenyl)-piperazin-1-yl...)
Affinity DataKi:  272nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50220503BDBM50220503(CHEMBL348890)
Affinity DataKi:  316nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458523BDBM50458523(JNJ-18038683)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]5-CT from recombinant rat 5-HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50395192BDBM50395192(CHEMBL2164336)
Affinity DataKi:  476nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510969BDBM50510969(CHEMBL4582321)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21393BDBM21393(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510970BDBM50510970(CHEMBL4521657)
Affinity DataKi:  562nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510967BDBM50510967(CHEMBL3139441)
Affinity DataKi:  700nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458526BDBM50458526(CHEMBL4205349 | US20240199555, Reference E55888)
Affinity DataKi:  700nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130279BDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  1.00E+3nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055575BDBM50055575(CHEMBL3321794)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
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