Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50007047
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50077257((4-Isopropyl-phenyl)-carbamic acid (S)-3a-methyl-1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human plasma BChE using s-butyrylthiocholine as substrate preincubated for 30 mins followed by substrate addition and measured after 25...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50246979(CHEMBL4105611 | US20230331674, Table 1.1)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine as substrate measured after 300 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50392999(CHEMBL2152545)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50392999(CHEMBL2152545)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505674(CHEMBL4458430)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505674(CHEMBL4458430)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505671(CHEMBL4567099)
Affinity DataIC50: 11nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505671(CHEMBL4567099)
Affinity DataIC50: 12nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505680(CHEMBL4457445)
Affinity DataIC50: 13nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505680(CHEMBL4457445)
Affinity DataIC50: 13nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505684(CHEMBL4566207)
Affinity DataIC50: 20nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505684(CHEMBL4566207)
Affinity DataIC50: 20nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505687(CHEMBL4538361)
Affinity DataIC50: 27nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505687(CHEMBL4538361)
Affinity DataIC50: 27nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505673(CHEMBL4467762)
Affinity DataIC50: 32nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505673(CHEMBL4467762)
Affinity DataIC50: 33nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505682(CHEMBL4583273)
Affinity DataIC50: 34nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505682(CHEMBL4583273)
Affinity DataIC50: 35nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505675(CHEMBL4440639)
Affinity DataIC50: 42nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505675(CHEMBL4440639)
Affinity DataIC50: 42nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505681(CHEMBL4454960)
Affinity DataIC50: 49nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505681(CHEMBL4454960)
Affinity DataIC50: 49nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505678(CHEMBL4559112)
Affinity DataIC50: 50nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505678(CHEMBL4559112)
Affinity DataIC50: 51nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505679(CHEMBL4554810)
Affinity DataIC50: 81nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505679(CHEMBL4554810)
Affinity DataIC50: 81nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505670(CHEMBL4553968)
Affinity DataIC50: 83nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505670(CHEMBL4553968)
Affinity DataIC50: 84nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50077257((4-Isopropyl-phenyl)-carbamic acid (S)-3a-methyl-1...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human erythrocyte AChE using acetyl-(beta-methyl)thiocholine as substrate preincubated for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505686(CHEMBL4530184)
Affinity DataIC50: 123nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505686(CHEMBL4530184)
Affinity DataIC50: 123nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505676(CHEMBL4457554)
Affinity DataIC50: 191nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505676(CHEMBL4457554)
Affinity DataIC50: 192nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50: 301nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 to 60 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505682(CHEMBL4583273)
Affinity DataIC50: 871nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505682(CHEMBL4583273)
Affinity DataIC50: 880nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505672(CHEMBL4437800)
Affinity DataIC50: 933nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505672(CHEMBL4437800)
Affinity DataIC50: 938nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505685(CHEMBL4554714)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505685(CHEMBL4554714)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505670(CHEMBL4553968)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505670(CHEMBL4553968)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 to 60 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505677(CHEMBL4469668)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505677(CHEMBL4469668)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50392999(CHEMBL2152545)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human erythrocyte AChE at 10 uM using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50392999(CHEMBL2152545)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human erythrocyte AChE at 10 uM using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505683(CHEMBL4516376)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50505683(CHEMBL4516376)
Affinity DataIC50: 7.77E+3nMAssay Description:Inhibition of human plasma BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50246979(CHEMBL4105611 | US20230331674, Table 1.1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse AChE using acetylthiocholine as substrate measured after 300 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed