Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50018445
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50608318(CHEMBL5279959)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human BTK (382 to 659 residues) expressed in baculovirus infected Sf21 insect cells preincubated for 15 mins followed by ATP addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50185178(1-tert-butyl-3-(3-(5-(4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of FGFR1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50420961(CHEMBL2088096)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232833(CHEMBL4076610)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50403060(CHEMBL2216830)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) incubated for 1 hr in presence of ATP by Z-LYTE enzymatic kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50403060(CHEMBL2216830)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) incubated for 1 hr in presence of ATP by Z-LYTE enzymatic kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50403060(CHEMBL2216830)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant FGFR3 (unknown origin) incubated for 1 hr in presence of ATP by Z-LYTE enzymatic kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232834(CHEMBL4063676)
Affinity DataIC50: 15nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50608316(CHEMBL5283952)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant FGFR1 using Poly (Glu, Tyr)4:1 as substrate incubated for 90 mins in presence of ATP by ELISA based spectrophotometer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50403060(CHEMBL2216830)
Affinity DataIC50: 189nMAssay Description:Inhibition of recombinant FGFR4 (unknown origin) incubated for 1 hr in presence of ATP by Z-LYTE enzymatic kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50608315(CHEMBL4089109)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) in presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50608314(CHEMBL4067901)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) in presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50608317(CHEMBL5282466)
Affinity DataIC50: 9.59E+3nMAssay Description:Inhibition of FGFR (unknown origin) using [gamma-33P]ATP as substrate incubated for 60 mins by Kinase-Glo Plus luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50291958(CHEMBL3314676)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of FGFR1 (unknown origin) using FAM-P22 as substrate incubated for 1 hr in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed