Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50012216
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555514BDBM50555514(CHEMBL4751485)
Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at CXCR4 in human CD4-positive T cells assessed as inhibition of CXCL12-induced calcium signal incubated for 20 mins by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035696BDBM50035696(AMD-3100 | CHEMBL18442 | 11-{4-[4,8, 11-1,4,8,11te...)
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity at CXCR4 in human CD4-positive T cells assessed as inhibition of CXCL12-induced calcium signal incubated for 20 mins by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555532BDBM50555532(CHEMBL4741926)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555530BDBM50555530(CHEMBL4763585)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555514BDBM50555514(CHEMBL4751485)
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555515BDBM50555515(CHEMBL4776865)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555550BDBM50555550(CHEMBL4742656)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555546BDBM50555546(CHEMBL4778921)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555533BDBM50555533(CHEMBL4756203)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555531BDBM50555531(CHEMBL4779872)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555537BDBM50555537(CHEMBL4741628)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555528BDBM50555528(CHEMBL4762425)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555534BDBM50555534(CHEMBL4749835)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555520BDBM50555520(CHEMBL4762385)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555545BDBM50555545(CHEMBL4757478)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555539BDBM50555539(CHEMBL4755917)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555521BDBM50555521(CHEMBL4741655)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555529BDBM50555529(CHEMBL4747341)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555542BDBM50555542(CHEMBL4788248)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555524BDBM50555524(CHEMBL4785495)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555516BDBM50555516(CHEMBL4784173)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555548BDBM50555548(CHEMBL4793397)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555525BDBM50555525(CHEMBL4744555)
Affinity DataIC50: 66nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555536BDBM50555536(CHEMBL4752542)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555549BDBM50555549(CHEMBL4797590)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458238BDBM50458238(CHEMBL4203703)
Affinity DataIC50: 88nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555526BDBM50555526(CHEMBL4749488)
Affinity DataIC50: 96nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555527BDBM50555527(CHEMBL4746043)
Affinity DataIC50: 101nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555540BDBM50555540(CHEMBL4796167)
Affinity DataIC50: 105nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555535BDBM50555535(CHEMBL4783171)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555541BDBM50555541(CHEMBL4761394)
Affinity DataIC50: 151nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200880BDBM50200880(2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5-methylfuran...)
Affinity DataIC50: 198nMAssay Description:Antagonist activity at CXCR1 (unknown origin) stably expressed in HEK293 cells assessed as reduction in IL-8-induced intracellular calcium change inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555518BDBM50555518(CHEMBL4788777)
Affinity DataIC50: 256nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555544BDBM50555544(CHEMBL4799317)
Affinity DataIC50: 293nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035696BDBM50035696(AMD-3100 | CHEMBL18442 | 11-{4-[4,8, 11-1,4,8,11te...)
Affinity DataIC50: 303nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555543BDBM50555543(CHEMBL4797285)
Affinity DataIC50: 792nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555519BDBM50555519(CHEMBL4763507)
Affinity DataIC50: 930nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555517BDBM50555517(CHEMBL4759222)
Affinity DataIC50: 1.29E+3nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555522BDBM50555522(CHEMBL4787898)
Affinity DataIC50: 2.44E+3nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555538BDBM50555538(CHEMBL4748070)
Affinity DataIC50: 2.89E+3nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555514BDBM50555514(CHEMBL4751485)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human ERG stably expressed in CHO cells after 4 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555523BDBM50555523(CHEMBL4796937)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555551BDBM50555551(CHEMBL4748971)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555547BDBM50555547(CHEMBL4747251)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed