Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50010570
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540263(CHEMBL4634992)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540268(CHEMBL4635399)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540268(CHEMBL4635399)
Affinity DataIC50: 10nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540268(CHEMBL4635399)
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50369724(HM71224 | Ly3337641 | Poseltinib)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540262(CHEMBL4645014)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540267(CHEMBL4639986)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US9987276, Compou...)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540266(CHEMBL4637985)
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540264(CHEMBL4645703)
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540265(CHEMBL4649751)
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540262(CHEMBL4645014)
Affinity DataIC50: 100nMAssay Description:Inhibition of BTK (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540264(CHEMBL4645703)
Affinity DataIC50: 100nMAssay Description:Inhibition of BTK (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540265(CHEMBL4649751)
Affinity DataIC50: 100nMAssay Description:Inhibition of BTK (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540266(CHEMBL4637985)
Affinity DataIC50: 100nMAssay Description:Inhibition of BTK (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540267(CHEMBL4639986)
Affinity DataIC50: 100nMAssay Description:Inhibition of BTK (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed