Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50018622
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610456(CHEMBL5288067)
Affinity DataIC50: 1nMAssay Description:Inhibition of RET V804M mutant (unknown origin) by invitro kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610456(CHEMBL5288067)
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGFR2 (unknown origin) by invitro kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610456(CHEMBL5288067)
Affinity DataIC50: 1nMAssay Description:Inhibition of RET (unknown origin) by invitro kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610455(CHEMBL5287428)
Affinity DataIC50: 15nMAssay Description:Inhibition of human P13KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAurora kinase A(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610452(CHEMBL5286283)
Affinity DataIC50: 35nMAssay Description:Inhibition of AURA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610454(CHEMBL5290094)
Affinity DataIC50: 102nMAssay Description:Inhibition of human EGFR phosphorylation by invitro enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610455(CHEMBL5287428)
Affinity DataIC50: 118nMAssay Description:Inhibition of human BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50610451(CHEMBL5272809)
Affinity DataIC50: 416nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610453(CHEMBL5277101)
Affinity DataIC50: 610nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610453(CHEMBL5277101)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50610452(CHEMBL5286283)
Affinity DataIC50: 8.23E+3nMAssay Description:Inhibition of mTOR (unknown origin) by ELISA based kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed