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Found 28 Enz. Inhib. hit(s) with all data for entry = 50010931
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543551(CHEMBL4633715)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of Aurora B in human SW620 cells assessed as reduction in histone H3 phosphorylation on Ser10 by Alexafluor-488 goat anti-rabbit antibody/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged Aurora A expressed in baculovirus expression system by enzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) by radioactive flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM12985(5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Aurora A (unknown origin) by biochemical kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50277584(CHEMBL482968 | N-(5-methyl-1H-pyrazol-3-yl)-6-(4-m...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human Aurora A using peptide substrate in presence of ATP at its Km concentration by Z-lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged Aurora B expressed in baculovirus expression system by enzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50243388(AT-9283 | US10981896, Compound AT9283)
Affinity DataIC50:  30nMAssay Description:Inhibition of Aurora B in human B-NHL cells assessed as inhibition of histone H3 phosphorylation on Ser10 by immunoblotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM12985(5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...)
Affinity DataIC50:  79nMAssay Description:Inhibition of Aurora B (unknown origin) by biochemical kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543547(CHEMBL4647086)
Affinity DataIC50:  90nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543544(CHEMBL4633273)
Affinity DataIC50:  143nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543547(CHEMBL4647086)
Affinity DataIC50:  152nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543548(CHEMBL4646357)
Affinity DataIC50:  164nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543543(CHEMBL4647800)
Affinity DataIC50:  172nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543549(CHEMBL4642258)
Affinity DataIC50:  175nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543544(CHEMBL4633273)
Affinity DataIC50:  189nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543549(CHEMBL4642258)
Affinity DataIC50:  190nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543545(CHEMBL4640055)
Affinity DataIC50:  220nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543548(CHEMBL4646357)
Affinity DataIC50:  220nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543542(CHEMBL4635731)
Affinity DataIC50:  230nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543546(CHEMBL4636044)
Affinity DataIC50:  260nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543550(CHEMBL4644226)
Affinity DataIC50:  272nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543542(CHEMBL4635731)
Affinity DataIC50:  320nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543543(CHEMBL4647800)
Affinity DataIC50:  360nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543546(CHEMBL4636044)
Affinity DataIC50:  458nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543545(CHEMBL4640055)
Affinity DataIC50:  538nMAssay Description:Inhibition of Aurora kinase B (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50543550(CHEMBL4644226)
Affinity DataIC50:  658nMAssay Description:Inhibition of Aurora kinase A (unknown origin) incubated for 30 mins by Kinase Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed