Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50018463
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human EGFR L858R/T790M mutant (696 to 1022 residues) expressed in insect sf9 cells in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human EGFR T790M mutant (696 to 1022 residues) expressed in insect sf9 cells in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSignal transducer and activator of transcription 3(Human)
West China Second University Hospital
Curated by ChEMBL
West China Second University Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human STAT3 expressed in human HepG2 cells incubated for 1.5 hrs by luciferase assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
West China Second University Hospital
Curated by ChEMBL
West China Second University Hospital
Curated by ChEMBL
Affinity DataIC50: 7.99E+3nMAssay Description:Inhibition of human STAT3 using Ac-pYLPQTV-NH2 peptide as substrate incubated for 24 hrs by Fluorescence polarization assayMore data for this Ligand-Target Pair
