Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50010801
TargetHistone deacetylase 6(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC6 (unknown origin) using acetyl-lysine tripeptide as substrate preincubated for 24 hrs followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human HDAC6 after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50506236(4sc-201 | BYK-408740 | BYK408740 | RAS-2410 | RAS2...)
Affinity DataIC50: 43nMAssay Description:Inhibition of C-terminal Flag-tagged HDAC1 (unknown origin) expressed in HEK293 cells or Sf21 cells using Ac-NH-GGK(Ac)-AMC peptide as substrate meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: 56nMAssay Description:Inhibition of human HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human HDAC1 after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50506236(4sc-201 | BYK-408740 | BYK408740 | RAS-2410 | RAS2...)
Affinity DataIC50: 72nMAssay Description:Inhibition of C-terminal Flag-tagged HDAC6 (unknown origin) expressed in HEK293 cells or Sf21 cells using Ac-NH-GGK(Ac)-AMC peptide as substrate meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50: 780nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50506236(4sc-201 | BYK-408740 | BYK408740 | RAS-2410 | RAS2...)
Affinity DataIC50: 877nMAssay Description:Inhibition of C-terminal Flag-tagged HDAC1 (unknown origin) expressed in HEK293 cells or Sf21 cells using Ac-RHK(Ac)K(Ac)-AMC peptide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50438390(CHEMBL2414000)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed