TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human PDE4B1 (1 to 736 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human PDE4B2 (152 to 487 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 148nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of human PDE7A1 (130 to 482 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 622nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of human PDE5A1 (535 to 860 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cGMP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE10A2 (449 to 770 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mi...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE2A (580 to 919 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cGMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetCytochrome P450 2B6(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2B6More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE9A2 (181 to 506 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cGMP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE1B (10 to 487 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE3A (679 to 1087 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE8A1 (480 to 820 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophysiologyMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A [559-660](Homo sapiens)
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair