Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50011825
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551532BDBM50551532(CHEMBL4744709)
Affinity DataIC50: 110nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551529BDBM50551529(CHEMBL4785863)
Affinity DataIC50: 180nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551519BDBM50551519(CHEMBL4799302)
Affinity DataIC50: 540nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551531BDBM50551531(CHEMBL4759640)
Affinity DataIC50: 680nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551533BDBM50551533(CHEMBL4797098)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit using Suc-LLVY-aminoluciferin as substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551518BDBM50551518(CHEMBL4749264)
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551528BDBM50551528(CHEMBL4744608)
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551513BDBM50551513(CHEMBL4783084)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551524BDBM50551524(CHEMBL4744941)
Affinity DataIC50: 4.16E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551510BDBM50551510(CHEMBL4789242)
Affinity DataIC50: 4.56E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551529BDBM50551529(CHEMBL4785863)
Affinity DataKd:  4.80E+3nMAssay Description:Binding affinity to immobilized human 20S proteasome beta 5 subunit by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551526BDBM50551526(CHEMBL4777718)
Affinity DataIC50: 5.63E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551525BDBM50551525(CHEMBL4791352)
Affinity DataIC50: 5.86E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551527BDBM50551527(CHEMBL4783452)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551515BDBM50551515(CHEMBL4762389)
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551509BDBM50551509(CHEMBL4784474)
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130010BDBM50130010(CHEMBL3275993)
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit using Suc-LLVY-aminoluciferin as substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551512BDBM50551512(CHEMBL4796028)
Affinity DataIC50: 8.25E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551522BDBM50551522(CHEMBL4753458)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551532BDBM50551532(CHEMBL4744709)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit using Z-nLPnLD-Glo as substrate incubated for 2 hrs followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551517BDBM50551517(CHEMBL4797661)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551523BDBM50551523(CHEMBL4757796)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551532BDBM50551532(CHEMBL4744709)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit using Z-LRR-Glo as substrate incubated for 2 hrs followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551532BDBM50551532(CHEMBL4744709)
Affinity DataKd:  1.70E+4nMAssay Description:Binding affinity to immobilized human 20S proteasome beta 5 subunit by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551520BDBM50551520(CHEMBL4784694)
Affinity DataIC50: 4.56E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551507BDBM50551507(CHEMBL4794342)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551516BDBM50551516(CHEMBL4782736)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551514BDBM50551514(CHEMBL4750732)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551530BDBM50551530(CHEMBL4764337)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551511BDBM50551511(CHEMBL4757556)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551508BDBM50551508(CHEMBL4760491)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551521BDBM50551521(CHEMBL4747824)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed