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Found 6 Enz. Inhib. hit(s) with all data for entry = 50011170
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Andhra University

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545410(CHEMBL4635395)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545411(CHEMBL4641594)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545412(CHEMBL4640592)
Affinity DataIC50:  4.13E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545413(CHEMBL4648824)
Affinity DataIC50:  4.48E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545410(CHEMBL4635395)
Affinity DataIC50:  5.81E+3nMAssay Description:Inhibition of PDE4 (unknown origin) assessed as inhibition of TNF-alpha releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed