Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50008005
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514792BDBM50514792(CHEMBL4519240)
Affinity DataIC50: 30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514792BDBM50514792(CHEMBL4519240)
Affinity DataIC50: 30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of ssRNA06-induced NF-kappaB activation measured after 24 hrs by quanti-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514809BDBM50514809(CHEMBL4530243)
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514806BDBM50514806(CHEMBL4452260)
Affinity DataIC50: 190nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514804BDBM50514804(CHEMBL4461378)
Affinity DataIC50: 210nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514792BDBM50514792(CHEMBL4519240)
Affinity DataKd:  225nMAssay Description:Binding affinity to human TLR8 ectodomain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514805BDBM50514805(CHEMBL4539893)
Affinity DataIC50: 290nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514797BDBM50514797(CHEMBL4451165)
Affinity DataIC50: 290nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514813BDBM50514813(CHEMBL4471285)
Affinity DataIC50: 350nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514796BDBM50514796(CHEMBL4535822)
Affinity DataIC50: 390nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514807BDBM50514807(CHEMBL4590994)
Affinity DataIC50: 390nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514818BDBM50514818(CHEMBL4585768)
Affinity DataIC50: 520nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514811BDBM50514811(CHEMBL4564658)
Affinity DataIC50: 550nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514799BDBM50514799(CHEMBL4445770)
Affinity DataIC50: 590nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514816BDBM50514816(CHEMBL4468868)
Affinity DataIC50: 600nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514800BDBM50514800(CHEMBL4449343)
Affinity DataIC50: 630nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514819BDBM50514819(CHEMBL4446241)
Affinity DataIC50: 800nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514821BDBM50514821(CHEMBL4451720)
Affinity DataIC50: 980nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514820BDBM50514820(CHEMBL4437576)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514801BDBM50514801(CHEMBL4473196)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514794BDBM50514794(CHEMBL4519304)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514812BDBM50514812(CHEMBL4564959)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514814BDBM50514814(CHEMBL4437700)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514802BDBM50514802(CHEMBL4584095)
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514803BDBM50514803(CHEMBL4547071)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514798BDBM50514798(CHEMBL4554556)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514795BDBM50514795(CHEMBL4475464)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514817BDBM50514817(CHEMBL4456082)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514815BDBM50514815(CHEMBL4438489)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514810BDBM50514810(CHEMBL4568317)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514808BDBM50514808(CHEMBL4444019)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514793BDBM50514793(CHEMBL4553074)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed