Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50010593
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540495(CHEMBL4127849 | acs.jmedchem.1c00409_ST.281)
Affinity DataIC50: 540nMAssay Description:Inhibition of wild-type full-length human liver FBPase expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malach...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human liver FBPase C38S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540495(CHEMBL4127849 | acs.jmedchem.1c00409_ST.281)
Affinity DataIC50: 640nMAssay Description:Inhibition of human liver FBPase C92S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540495(CHEMBL4127849 | acs.jmedchem.1c00409_ST.281)
Affinity DataIC50: 670nMAssay Description:Inhibition of human liver FBPase C179S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540495(CHEMBL4127849 | acs.jmedchem.1c00409_ST.281)
Affinity DataIC50: 850nMAssay Description:Inhibition of human liver FBPase C116S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 980nMAssay Description:Inhibition of human liver FBPase C92S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human liver FBPase C281S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540495(CHEMBL4127849 | acs.jmedchem.1c00409_ST.281)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human liver FBPase C183S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human liver FBPase C92S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human liver FBPase C183S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human liver FBPase C116S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540495(CHEMBL4127849 | acs.jmedchem.1c00409_ST.281)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human liver FBPase C281S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of wild-type full-length human liver FBPase expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malach...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human liver FBPase C281S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human liver FBPase C183S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of wild-type full-length human liver FBPase expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malach...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human liver FBPase C179S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human liver FBPase C179S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human liver FBPase C116S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540495(CHEMBL4127849 | acs.jmedchem.1c00409_ST.281)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human liver FBPase C38S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human liver FBPase C38S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540496(CHEMBL4635138)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human liver FBPase C128S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50540495(CHEMBL4127849 | acs.jmedchem.1c00409_ST.281)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human liver FBPase C128S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human liver FBPase C128S mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate incubated for 5 mins by malachite green...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed