Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50010623
TargetIntegrase(Human immunodeficiency virus 1)
Irbm

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50:  27nMAssay Description:Inhibition of wild type recombinant HIV1 His6-tagged integrase expressed in Escherichia coli BL21 using 18 nucleotide 3'-biotin labeled DNA acceptor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540670(CHEMBL4633550)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of Tracer Red from human ERG measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540671(CHEMBL4635907)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of Tracer Red from human ERG measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540668(CHEMBL4637717)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP1A2 expressed in baculovirus infected insect cells using luciferin-1A2 as substrate preincubated with enzyme-substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540669(CHEMBL4637524)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP1A2 expressed in baculovirus infected insect cells using luciferin-1A2 as substrate preincubated with enzyme-substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540670(CHEMBL4633550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP1A2 expressed in baculovirus infected insect cells using luciferin-1A2 as substrate preincubated with enzyme-substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540671(CHEMBL4635907)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP1A2 expressed in baculovirus infected insect cells using luciferin-1A2 as substrate preincubated with enzyme-substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540668(CHEMBL4637717)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP2D6 expressed in baculovirus infected insect cells using luciferin-ME as substrate preincubated with enzyme/substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540669(CHEMBL4637524)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP2D6 expressed in baculovirus infected insect cells using luciferin-ME as substrate preincubated with enzyme/substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540670(CHEMBL4633550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP2D6 expressed in baculovirus infected insect cells using luciferin-ME as substrate preincubated with enzyme/substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540671(CHEMBL4635907)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP2D6 expressed in baculovirus infected insect cells using luciferin-ME as substrate preincubated with enzyme/substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540668(CHEMBL4637717)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP3A4 expressed in baculovirus infected insect cells using luciferin-IPA as substrate preincubated with enzyme/substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540669(CHEMBL4637524)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP3A4 expressed in baculovirus infected insect cells using luciferin-IPA as substrate preincubated with enzyme/substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540670(CHEMBL4633550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP3A4 expressed in baculovirus infected insect cells using luciferin-IPA as substrate preincubated with enzyme/substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540671(CHEMBL4635907)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human microsomal CYP3A4 expressed in baculovirus infected insect cells using luciferin-IPA as substrate preincubated with enzyme/substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540668(CHEMBL4637717)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of Tracer Red from human ERG measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50540669(CHEMBL4637524)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of Tracer Red from human ERG measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed