Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 50010883
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543063(CHEMBL4641635)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543093(CHEMBL4640081)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543103(CHEMBL4644237)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543064(CHEMBL4633425)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543096(CHEMBL4640713)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543067(CHEMBL4645822)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543074(CHEMBL4644445)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543100(CHEMBL4632970)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543065(CHEMBL4633266)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543097(CHEMBL4632604)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543077(CHEMBL4642802)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543101(CHEMBL4635942)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543073(CHEMBL4646316)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543066(CHEMBL4640571)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543079(CHEMBL4634579)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543085(CHEMBL4643040)
Affinity DataIC50:  3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543094(CHEMBL4641876)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543069(CHEMBL4645263)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543092(CHEMBL4637007)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543091(CHEMBL4646419)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543095(CHEMBL4636353)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543075(CHEMBL4649866)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543104(CHEMBL4647130)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543070(CHEMBL4632381)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543068(CHEMBL4647937)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543086(CHEMBL4637855)
Affinity DataIC50:  6nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543080(CHEMBL4636770)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543071(CHEMBL4632947)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543105(CHEMBL4636828)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543076(CHEMBL4640237)
Affinity DataIC50:  8nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543090(CHEMBL4636153)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543078(CHEMBL4641605)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543099(CHEMBL4639269)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543100(CHEMBL4632970)
Affinity DataIC50:  12nMAssay Description:Inhibition of PI3Kalpha in human BT474 cells expressing P3KCA mutant assessed as reduction in AKT phosphorylation at residue S473 incubated for 2 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543083(CHEMBL4640912)
Affinity DataIC50:  12nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543084(CHEMBL4636882)
Affinity DataIC50:  14nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543089(CHEMBL4645130)
Affinity DataIC50:  19nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543082(CHEMBL4649475)
Affinity DataIC50:  20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543072(CHEMBL4635365)
Affinity DataIC50:  20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543098(CHEMBL4635508)
Affinity DataIC50:  21nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543102(CHEMBL4636844)
Affinity DataIC50:  23nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543081(CHEMBL4649361)
Affinity DataIC50:  26nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543106(CHEMBL4643419)
Affinity DataIC50:  26nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543087(CHEMBL4647286)
Affinity DataIC50:  30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543100(CHEMBL4632970)
Affinity DataIC50:  183nMAssay Description:Inhibition of PI3Kdelta in human Jeko1 cells assessed as reduction in AKT phosphorylation at residue S473 measured after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543088(CHEMBL4644072)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS peptide as substrate preincubated for 15 mins followed by ATP addition at Km concentration an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543100(CHEMBL4632970)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of PI3Kbeta in human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at residue S473 measured after 30 mins by sandwich ELIS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543100(CHEMBL4632970)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 10 mins followed by NADPH addition and measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Mus musculus (Mouse))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543100(CHEMBL4632970)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as reduction in AKT phosphorylation at residue S473 treated with mouse C5a component and mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Luoxin Pharmaceutical (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50543100(CHEMBL4632970)
Affinity DataIC50:  2.16E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using s-mephenytoin as substrate preincubated for 10 mins followed by NADPH addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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