Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50010923
LigandPNGBDBM50303748((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-phenyl)-...)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50303760((R)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-phenyl)-...)
Affinity DataEC50:  16nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
LigandPNGBDBM50543445(CHEMBL4646904)
Affinity DataEC50:  56nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50543446(CHEMBL4634826)
Affinity DataEC50:  12nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50543447(CHEMBL4641267)
Affinity DataEC50:  90nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50303760((R)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-phenyl)-...)
Affinity DataEC50:  4.60E+3nMAssay Description:Inhibition of PRMT5 in human MCF7 cells assessed as reduction in symmetrically dimethylated nuclear protein level incubated for 3 days by Alexafluor-...More data for this Ligand-Target Pair
LigandPNGBDBM50543449(CHEMBL4643667)
Affinity DataEC50:  220nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50543450(CHEMBL4636476)
Affinity DataEC50:  240nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50543451(CHEMBL4647445)
Affinity DataEC50:  50nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50543452(CHEMBL4648344)
Affinity DataEC50:  66nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50543453(CHEMBL4649422)
Affinity DataEC50:  68nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50543448(CHEMBL4648777)
Affinity DataEC50:  620nMAssay Description:Inhibition of recombinant Avi-tagged PRMT5 (2 to 637)/ His-tagged MEP50 (2 to 342) (unknown origin) expressed in baculovirus infected Sf21 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed