Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50010925
TargetRho-associated protein kinase 2(Human)
Banasthali Vidyapith

Curated by ChEMBL
LigandPNGBDBM50543454(CHEMBL4634858)
Affinity DataIC50: 8nMAssay Description:Inhibition of ROCK2 (unknown origin) assessed as phosphorylation of MYPT1 using Tetramethylbenzidine as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Banasthali Vidyapith

Curated by ChEMBL
LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of ROCK2 (unknown origin) assessed as phosphorylation of MYPT1 using Tetramethylbenzidine as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Banasthali Vidyapith

Curated by ChEMBL
LigandPNGBDBM50543455(CHEMBL4635281)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of ROCK2 (unknown origin) assessed as phosphorylation of MYPT1 using Tetramethylbenzidine as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Banasthali Vidyapith

Curated by ChEMBL
LigandPNGBDBM50543456(CHEMBL4633684)
Affinity DataIC50: 9nMAssay Description:Inhibition of ROCK2 (unknown origin) assessed as phosphorylation of MYPT1 using Tetramethylbenzidine as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed