Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50017946
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50223891((S)-3-[3'-(2-cyclopropylamino-3,4-dioxo-cyclobut-1...)
Affinity DataKi:  0.5nMAssay Description:Antagonist activity at human alphaVbeta3 Integrin assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50606463(CHEMBL5220250)
Affinity DataIC50:  2nMAssay Description:Inhibition of human AchE by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50236053((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human CXCR1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50606464(CHEMBL5219098)
Affinity DataIC50:  13nMAssay Description:Inhibition of human AchE by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50187003(3-(3,4-dioxo-2-(pentan-3-ylamino)cyclobut-1-enylam...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human CXCR1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50187003(3-(3,4-dioxo-2-(pentan-3-ylamino)cyclobut-1-enylam...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human CXCR2-mediated chemotaxis expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50606464(CHEMBL5219098)
Affinity DataIC50:  21nMAssay Description:Inhibition of human BchE by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50400844(CHEMBL2205685)
Affinity DataIC50:  24nMAssay Description:Inhibition of Angiotensin 2 binding to Angiotensin 2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50606462(CHEMBL5219534)
Affinity DataIC50:  25nMAssay Description:Inhibition of Angiotensin 2 binding to Angiotensin 2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM86494(EAA-090 | Perzinfotel | WAY-126090)
Affinity DataIC50:  30nMAssay Description:Binding affinity to NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50187001(3-(2-hydroxy-4-nitrophenylamino)-4-(phenylamino)cy...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human CXCR1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50606463(CHEMBL5220250)
Affinity DataIC50:  110nMAssay Description:Inhibition of human BchE by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50606460(CHEMBL145806)
Affinity DataIC50:  470nMAssay Description:Binding affinity to NMDA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50606461(CHEMBL83688)
Affinity DataIC50:  470nMAssay Description:Binding affinity to NMDA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM86494(EAA-090 | Perzinfotel | WAY-126090)
Affinity DataIC50:  7.60E+3nMAssay Description:Binding affinity to TCP-stimulated NMDA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50606465(CHEMBL5220101)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of MMP-1 (unknown origin) using DnpPro-Cha-Gly-Cys(Me)-His-Ala-Lys(Nma)-NH2 as substrate by fluorescence spectroscopyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50200878((R)-3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocycl...)
Affinity DataKd:  0.0490nMAssay Description:Binding affinity to human CXCR2 assessed as dissociation constant incubated for 6 to 24 hrs by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50200878((R)-3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocycl...)
Affinity DataKd:  3.90nMAssay Description:Binding affinity to human CXCR1 assessed as dissociation constant incubated for 6 to 24 hrs by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed