Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50012922
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561600BDBM50561600(CHEMBL4788488)
Affinity DataKi:  0.280nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299701BDBM50299701(N6-Methyl-2-phenylethynyl-5'-N-methylcarboxamidoad...)
Affinity DataKi:  0.440nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069812BDBM50069812(CHEMBL3407784)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561595BDBM50561595(CHEMBL4755127)
Affinity DataKi:  0.75nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561602BDBM50561602(CHEMBL4752619)
Affinity DataKi:  0.896nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561598BDBM50561598(CHEMBL4791368)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21221BDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50118812BDBM50118812(CHEMBL119709 | (3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-io...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561596BDBM50561596(CHEMBL4795767)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561603BDBM50561603(CHEMBL4764532)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50389148BDBM50389148(CHEMBL2064657)
Affinity DataKi:  3.5nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561597BDBM50561597(CHEMBL4800206)
Affinity DataKi:  8.5nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561599BDBM50561599(CHEMBL4758462)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561598BDBM50561598(CHEMBL4791368)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]AB-MECA from mouse adrenergic A3 receptor expressed in HEK293 cell membranes assessed as inhibitor constant by radio ligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561603BDBM50561603(CHEMBL4764532)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]AB-MECA from mouse adrenergic A3 receptor expressed in HEK293 cell membranes assessed as inhibitor constant by radio ligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561601BDBM50561601(CHEMBL4742689)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561602BDBM50561602(CHEMBL4752619)
Affinity DataKi:  37nMAssay Description:Displacement of [125I]AB-MECA from mouse adrenergic A3 receptor expressed in HEK293 cell membranes assessed as inhibitor constant by radio ligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561600BDBM50561600(CHEMBL4788488)
Affinity DataKi:  85nMAssay Description:Displacement of [125I]AB-MECA from mouse adrenergic A3 receptor expressed in HEK293 cell membranes assessed as inhibitor constant by radio ligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236779BDBM50236779(CHEMBL4086593)
Affinity DataKi:  315nMAssay Description:Displacement of [125I]AB-MECA from recombinant mouse A1AR expressed in HEK293 cells assessed as inhibitory constant by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561597BDBM50561597(CHEMBL4800206)
Affinity DataKi:  369nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1AR receptor expressed in HEK293 cells assessed as inhibitory constant by radio ligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561596BDBM50561596(CHEMBL4795767)
Affinity DataKi:  432nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1AR receptor expressed in HEK293 cells assessed as inhibitory constant by radio ligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561597BDBM50561597(CHEMBL4800206)
Affinity DataKi:  435nMAssay Description:Displacement of [125I]AB-MECA from mouse adrenergic A3 receptor expressed in HEK293 cell membranes assessed as inhibitor constant by radio ligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561599BDBM50561599(CHEMBL4758462)
Affinity DataKi:  625nMAssay Description:Displacement of [125I]AB-MECA from mouse adrenergic A3 receptor expressed in HEK293 cell membranes assessed as inhibitor constant by radio ligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116877BDBM50116877(CHEMBL3612941)
Affinity DataKi:  760nMAssay Description:Displacement of [3H]-LSD from recombinant human 5HT2B receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561598BDBM50561598(CHEMBL4791368)
Affinity DataKi:  838nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarboxamidoadenosine from human A2A receptor expressed in HEK293 cells assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561599BDBM50561599(CHEMBL4758462)
Affinity DataKi:  864nMAssay Description:Displacement of [125I]AB-MECA from recombinant mouse A1AR expressed in HEK293 cells assessed as inhibitory constant by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236779BDBM50236779(CHEMBL4086593)
Affinity DataKi:  1.16E+3nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1AR receptor expressed in HEK293 cells assessed as inhibitory constant by radio ligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561601BDBM50561601(CHEMBL4742689)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]AB-MECA from mouse adrenergic A3 receptor expressed in HEK293 cell membranes assessed as inhibitor constant by radio ligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561596BDBM50561596(CHEMBL4795767)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [125I]AB-MECA from mouse adrenergic A3 receptor expressed in HEK293 cell membranes assessed as inhibitor constant by radio ligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561599BDBM50561599(CHEMBL4758462)
Affinity DataKi:  1.67E+3nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1AR receptor expressed in HEK293 cells assessed as inhibitory constant by radio ligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561597BDBM50561597(CHEMBL4800206)
Affinity DataKi:  2.46E+3nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarboxamidoadenosine from human A2A receptor expressed in HEK293 cells assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561600BDBM50561600(CHEMBL4788488)
Affinity DataKi:  3.26E+3nMAssay Description:Displacement of [125I]AB-MECA from recombinant mouse A1AR expressed in HEK293 cells assessed as inhibitory constant by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116877BDBM50116877(CHEMBL3612941)
Affinity DataKi:  3.94E+3nMAssay Description:Displacement of [3H]-Win35428 from human recombinant DAT receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561598BDBM50561598(CHEMBL4791368)
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1AR receptor expressed in HEK293 cells assessed as inhibitory constant by radio ligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236785BDBM50236785(CHEMBL4090355)
Affinity DataKi:  4.17E+3nMAssay Description:Displacement of [125I]AB-MECA from recombinant mouse A1AR expressed in HEK293 cells assessed as inhibitory constant by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561600BDBM50561600(CHEMBL4788488)
Affinity DataKi:  4.62E+3nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarboxamidoadenosine from human A2A receptor expressed in HEK293 cells assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed