Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50011417
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547671(CHEMBL4778125)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of wild-type ALK (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of wild-type ALK (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547671(CHEMBL4778125)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of ALK L1196M (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547670(CHEMBL4779513)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of wild-type ALK (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of ALK L1196M (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547670(CHEMBL4779513)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of ALK L1196M (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547669(CHEMBL4756753)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of wild-type ALK (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547672(CHEMBL4758571)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of wild-type ALK (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547669(CHEMBL4756753)
Affinity DataIC50: 12nMAssay Description:Inhibition of ALK L1196M (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547672(CHEMBL4758571)
Affinity DataIC50: 13nMAssay Description:Inhibition of ALK L1196M (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed