Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50011610
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549241(CHEMBL4764582)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549254(CHEMBL4745104)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549242(CHEMBL4797475)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM395296(N-[2-(3-Hydroxy-3-methylbutyl)-6-(2-hydroxypropan-...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549262(CHEMBL4777489)
Affinity DataIC50: 11nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549263(CHEMBL4782731)
Affinity DataIC50: 17nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549255(CHEMBL4754306)
Affinity DataIC50: 35nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549259(CHEMBL4799896)
Affinity DataIC50: 37nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549244(CHEMBL4747510)
Affinity DataIC50: 41nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549257(CHEMBL4761337)
Affinity DataIC50: 47nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 55nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549258(CHEMBL4779374)
Affinity DataIC50: 57nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549254(CHEMBL4745104)
Affinity DataIC50: 59nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549245(CHEMBL4781524)
Affinity DataIC50: 96nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549242(CHEMBL4797475)
Affinity DataIC50: 110nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549256(CHEMBL4798349)
Affinity DataIC50: 113nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549241(CHEMBL4764582)
Affinity DataIC50: 125nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM395296(N-[2-(3-Hydroxy-3-methylbutyl)-6-(2-hydroxypropan-...)
Affinity DataIC50: 128nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549260(CHEMBL4746200)
Affinity DataIC50: 128nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549252(CHEMBL4800602)
Affinity DataIC50: 170nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549261(CHEMBL4782761)
Affinity DataIC50: 176nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549255(CHEMBL4754306)
Affinity DataIC50: 198nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549250(CHEMBL4750612)
Affinity DataIC50: 202nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549245(CHEMBL4781524)
Affinity DataIC50: 223nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549258(CHEMBL4779374)
Affinity DataIC50: 256nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549249(CHEMBL4746921)
Affinity DataIC50: 309nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549244(CHEMBL4747510)
Affinity DataIC50: 375nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549263(CHEMBL4782731)
Affinity DataIC50: 514nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549257(CHEMBL4761337)
Affinity DataIC50: 730nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549262(CHEMBL4777489)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549248(CHEMBL4763127)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549247(CHEMBL4776639)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549246(CHEMBL4780645)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549259(CHEMBL4799896)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549253(CHEMBL4787177)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549251(CHEMBL4790546)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM395296(N-[2-(3-Hydroxy-3-methylbutyl)-6-(2-hydroxypropan-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549241(CHEMBL4764582)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549241(CHEMBL4764582)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549242(CHEMBL4797475)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549242(CHEMBL4797475)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
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