Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50012354
TargetKelch-like ECH-associated protein 1(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556867BDBM50556867(CHEMBL4757224)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKelch-like ECH-associated protein 1(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556867BDBM50556867(CHEMBL4757224)
Affinity DataKd:  4.10E+3nMAssay Description:Binding affinity to Keap1 Kelch domain (321 to 609 residues) (unknown origin) by SPR based direct binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556867BDBM50556867(CHEMBL4757224)
Affinity DataKd:  4.10E+3nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556866BDBM50556866(CHEMBL4753898)
Affinity DataKd:  2.09E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556862BDBM50556862(CHEMBL4778827)
Affinity DataKd:  2.37E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556864BDBM50556864(CHEMBL4750672)
Affinity DataKd:  2.70E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556869BDBM50556869(CHEMBL4743973)
Affinity DataKd:  4.06E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556863BDBM50556863(CHEMBL4749813)
Affinity DataKd: >5.00E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556861BDBM50556861(CHEMBL4794824)
Affinity DataKd: >5.00E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556860BDBM50556860(CHEMBL4757116)
Affinity DataKd: >5.00E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556859BDBM50556859(CHEMBL4764629)
Affinity DataKd: >5.00E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556871BDBM50556871(CHEMBL4780159)
Affinity DataKd: >5.00E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556870BDBM50556870(CHEMBL4780450)
Affinity DataKd: >5.00E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556868BDBM50556868(CHEMBL4764486)
Affinity DataKd: >5.00E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556865BDBM50556865(CHEMBL4758421)
Affinity DataKd: >5.00E+5nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed