Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50013833
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM517533(USRE48711, Example 140 | 4-(4-cyclopropyl-1H-imida...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570214(CHEMBL4855907)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50212258(GS-4997 | Selonsertib)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50505936(CHEMBL4466569)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant ASK1 (654 to 971 residues) expressed in baculovirus-infected Sf21 cells using GST-fused MAP2K7 as substrate in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570211(CHEMBL4870142)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570209(CHEMBL4845717)
Affinity DataIC50: 23nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570212(CHEMBL4861744)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570200(CHEMBL4855351)
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570202(CHEMBL4879378)
Affinity DataIC50: 38nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570208(CHEMBL4878410)
Affinity DataIC50: 39nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570195(CHEMBL4853834)
Affinity DataIC50: 41nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570201(CHEMBL4870487)
Affinity DataIC50: 54nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570213(CHEMBL4850703)
Affinity DataIC50: 66nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570205(CHEMBL4873038)
Affinity DataIC50: 69nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570204(CHEMBL4847905)
Affinity DataIC50: 74nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570198(CHEMBL4848718)
Affinity DataIC50: 88nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570207(CHEMBL4854772)
Affinity DataIC50: 90nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570203(CHEMBL4866091)
Affinity DataIC50: 91nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570196(CHEMBL4868746)
Affinity DataIC50: 125nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570199(CHEMBL4846465)
Affinity DataIC50: 143nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570191(CHEMBL4846965)
Affinity DataIC50: 152nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570210(CHEMBL4852337)
Affinity DataIC50: 153nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570206(CHEMBL4846645)
Affinity DataIC50: 240nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570194(CHEMBL4851548)
Affinity DataIC50: 506nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570197(CHEMBL4878207)
Affinity DataIC50: 743nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570192(CHEMBL4876111)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570193(CHEMBL4874376)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length ASK1 expressed in baculovirus-infected Sf21 cells using STK-Substrate-3 biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed