Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50013849
TargetCystic fibrosis transmembrane conductance regulator(Human)
National Research Council (Itb-Cnr)

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataKd:  2.56E+4nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
National Research Council (Itb-Cnr)

Curated by ChEMBL
LigandPNGBDBM50289703(Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...)
Affinity DataKd:  4.78E+4nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
National Research Council (Itb-Cnr)

Curated by ChEMBL
LigandPNGBDBM50217942(3-Rhamnoglucosylquercetin | cid_5280805 | CHEMBL22...)
Affinity DataKd:  6.58E+4nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
National Research Council (Itb-Cnr)

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataKd:  1.75E+5nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
National Research Council (Itb-Cnr)

Curated by ChEMBL
LigandPNGBDBM50043280(4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimi...)
Affinity DataKd:  1.89E+5nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed