Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50015596
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50587725(CHEMBL1615434)
Affinity DataIC50: 110nMAssay Description:Inhibition of LSD1 (unknown origin) by Spectra Max Paradigm Microplate Reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50986(SMR000232286 | MLS000563434 | cid_160876)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 using H3K4me2 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50587726(CHEMBL3401107)
Affinity DataIC50: 183nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) transfected in Escherichia coli BL21 (DE) using H3Kme2 as a substrate incubated for 30 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50226664(2-hydroxy-3,9,10-trimethoxy-5,6-dihydroisoquino[3,...)
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 using H3K4me2 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM20461(Zostrix | (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl...)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) using 10-acetyl-3,7-dihydroxyphenoxazine fluorometric substrate measured after 30 mins by multiplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50226670(jatrorrhizine | CHEMBL251055)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 using H3K4me2 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as a substrate measured after 0.5 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 6.97E+3nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 using H3K4me2 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM57938(cid_160254 | MLS001049002 | (1R)-1,6,6-trimethyl-2...)
Affinity DataIC50: 9.02E+3nMAssay Description:Inhibition of LSD1 (unknown origin) by Spectra Max Paradigm Microplate Reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50292332(CHEMBL1270849 | 2,3,9,10-tetramethoxy-5,6-dihydro-...)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 using H3K4me2 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50423877(Dihydrotanshinone I | DIHYDROTANSHINONE | acs.jmed...)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of LSD1 (unknown origin) by Spectra Max Paradigm Microplate Reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM51317(1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of LSD1 (unknown origin) by Spectra Max Paradigm Microplate Reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Beijing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50133496(Rosmarinic acid, 2 | cid_5281792 | CHEMBL324842 | ...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of LSD1 (unknown origin) by Spectra Max Paradigm Microplate Reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed